The human RAB genes share structural and biochemical properties with the Ras gene superfamily, and RAB4(synonym: RAB4A) is a small GTPase belonging to this Ras superfamily. Accumulating data suggests an important role for RAB proteins either in endocytosis or in biosynthetic protein transport. The transport of newly synthesized proteins from endoplasmic reticulum to the Golgi complex and to secretory vesicles involves the movement of carrier vesicles, a process that appears to involve RAB protein function. RAB4 may also function as regulator along the receptor recycling pathway.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Protein transport. Probably involved in vesicular traffic (By similarity).
Host
Rabbit
Immunogen
RAB4A, member RAS oncogene family
Isotype
IgG
Molecular Weight
26 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
HRES 1/RAB4, RAB4, RAB4A, Ras related protein Rab 4A
Uniprot
P20338
Gene Id
5867
Research Area
Signal Transduction, Neuroscience
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)