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Home / Primary Antibodies / Polyclonal Antibodies

RAB1B antibody

SKU : BHA10806993

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Mfr.No.	FNab07001
Background	Members of the RAB protein family, such as RAB1B, are low molecular mass monomeric GTPases localized on the cytoplasmic surfaces of distinct membrane-bound organelles. RAB1B functions in the early secretory pathway and is essential for vesicle transport between the endoplasmic reticulum (ER) and Golgi (Chen et al., 1997 (PubMed 9030196); Alvarez et al., 2003 (PubMed 12802079)).
Categories	Primary Antibodies
Clonality	polyclonal
Description	The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1B regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments. Plays a role in the initial events of the autophagic vacuole development which take place at specialized regions of the endoplasmic reticulum.
Host	Rabbit
Immunogen	RAB1B, member RAS oncogene family
Isotype	IgG
Molecular Weight	22 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	RAB1B, Ras related protein Rab 1B

Uniprot	Q9H0U4
Gene Id	81876
Research Area	Signal Transduction

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IF
Description	ELISA ; WB ; IF
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab07001.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10806993	FNab07001	100ug	$260		Add to Cart

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