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Home / Antibodies

Pyruvate Kinase Antibody / PKM2

SKU : BHA17102623

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NSJ Bioreagents

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Mfr.No.	F54017
Clonality	Monoclonal
Description	Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio betwween the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival. (UniProt)
Formulation	Antibody in PBS with 50% Glycerol and 0.03% ProClin 300
Host	Mouse
Immunogen Region	A human recombinant partial protein was used as the immunogen for this PKM2 antibody.
Isotype	IgG1
Predicted Reactivity	Human, Mouse, Rat, Primate
Reactivity	Primate, Human, Mouse, Rat
Recombinant	No

Antigen	Pyruvate Kinase
Uniprot	P14618
Clone No	1A7-G6-H6

Format	Purified
Purification	Protein G affinity
Storage	Store the PKM2 antibody at -20°C.

Applications	WB, ICC, IF
Dilution	Western blot: 1:1000,ICC/Immunofluorescence: 1:400

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17102623	F54017	0.1 ml	$379		Add to Cart

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