Cell surface receptor for NECTIN2. May act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. Following interaction with NECTIN2, inhibits T-cell proliferation. Competes with CD226 for NECTIN2-binding.
Categories
Primary Antibodies
Clonality
polyclonal
Host
Rabbit
Immunogen
poliovirus receptor related immunoglobulin domain containing
Isotype
IgG
Molecular Weight
34kd
Reactivity
Human
Regulatory
RUO
Synonyms
C7orf15,CD112R, PVRIG, Transmembrane protein PVRIG
Uniprot
Q6DKI7
Gene Id
79037
Research Area
Immunology
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)