Sequesters mitogen-activated protein kinases(MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus(By similarity).
Categories
Primary Antibodies
Clonality
polyclonal
Description
Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus (By similarity).
Host
Rabbit
Immunogen
protein tyrosine phosphatase, receptor type, R
Isotype
IgG
Molecular Weight
32 kDa,47 kDa,65 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
ECPTP, PTPRQ
Uniprot
Q15256
Gene Id
5801
Research Area
Developmental biology, Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)