Plays a role in sorting of endocytic ubiquitinated cargos into multivesicular bodies(MVBs) via its interaction with the ESCRT-I complex(endosomal sorting complex required for transport I), and possibly also other ESCRT complexes. May act as a negative regulator of Ras-mediated mitogenic activity. Plays a role in ciliogenesis.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Plays a role in sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs) via its interaction with the ESCRT-I complex (endosomal sorting complex required for transport I), and possibly also other ESCRT complexes. May act as a negative regulator of Ras-mediated mitogenic activity. Plays a role in ciliogenesis.
Host
Rabbit
Immunogen
protein tyrosine phosphatase, non-receptor type 23
Isotype
IgG
Molecular Weight
179 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
KIAA1471
Uniprot
Q9H3S7
Gene Id
25930
Research Area
Signal Transduction, Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)