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Home / Primary Antibodies / Polyclonal Antibodies

PTN antibody

SKU : BHA10806918

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Mfr.No.	FNab06926
Alternative Names	HBNF1 ; NEGF1
Background	The protein encoded by this gene is a secreted heparin-binding growth factor. The protein has significant roles in cell growth and survival, cell migration, angiogenesis and tumorigenesis. Alternative splicing and the use of alternative promoters results in multiple transcript variants.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells (PubMed:1768439, PubMed:1733956). Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation (PubMed:11278720). Binds to cell-surface target proteins via their chondroitin sulfate groups (PubMed:26896299). Down-regulates PTPRZ1 activity (PubMed:16814777).
Host	Rabbit
Immunogen	pleiotrophin
Isotype	IgG
Molecular Weight	17 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	HBNF1, NEGF1

Uniprot	P21246
Gene Id	5764
Research Area	Developmental biology, Signal Transduction, Neuroscience

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC
Description	ELISA ; WB ; IHC
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab06926.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10806918	FNab06926	100ug	$240		Add to Cart

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