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Home / Primary Antibodies / Polyclonal Antibodies

PTHLH antibody

SKU : BHA10806914

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Mfr.No.	FNab06922
Alternative Names	PTHRP
Categories	Primary Antibodies
Clonality	polyclonal
Description	Neuroendocrine peptide which is a critical regulator of cellular and organ growth, development, migration, differentiation and survival and of epithelial calcium ion transport. Regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. Required for skeletal homeostasis. Promotes mammary mesenchyme differentiation and bud outgrowth by modulating mesenchymal cell responsiveness to BMPs. Upregulates BMPR1A expression in the mammary mesenchyme and this increases the sensitivity of these cells to BMPs and allows them to respond to BMP4 in a paracrine and/or autocrine fashion. BMP4 signaling in the mesenchyme, in turn, triggers epithelial outgrowth and augments MSX2 expression, which causes the mammary mesenchyme to inhibit hair follicle formation within the nipple sheath (By similarity). Promotes colon cancer cell migration and invasion in an integrin alpha-6/beta-1- dependent manner through activation of Rac1. Osteostatin is a potent inhibitor of osteoclastic bone resorption.
Host	Rabbit
Immunogen	parathyroid hormone-like hormone
Isotype	IgG
Molecular Weight	19-24 kDa
Reactivity	Human, Rat
Regulatory	RUO
Synonyms	PTHRP

Uniprot	P12272
Gene Id	5744

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.1% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB
Description	ELISA ; WB
Tested Application	WB: 1:500-1:2000

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SKU	Supplier No.	Size	Your price	Quantity
BHA10806914	FNab06922	100ug	$280		Add to Cart

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