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Home / Primary Antibodies / Polyclonal Antibodies

PSMD3 antibody

SKU : BHA10806880

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Mfr.No.	FNab06888
Background	The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the proteasome subunit S3 family that functions as one of the non-ATPase subunits of the 19S regulator lid. Single nucleotide polymorphisms in this gene are associated with neutrophil count.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
Host	Rabbit
Immunogen	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
Isotype	IgG
Molecular Weight	65 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO

Uniprot	O43242
Gene Id	5709
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, IP
Description	ELISA ; WB ; IHC ; IP
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab06888.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10806880	FNab06888	100ug	$240		Add to Cart

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