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Home / Primary Antibodies

PrP Antibody Prion protein (R30892)

SKU : BHA17104432

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Mfr.No.	R30892
Clonality	Polyclonal
Description	Prion protein, also known as CD230 and PrP, is a protein that in humans is encoded by the PRNP gene. Expression is predominantly in the nervous system but occurs to some degree in many other tissues throughout the body. Puckett et al.(1991)identified a RFLP with a high degree of heterozygosity in the 5-prime region of the PRNP gene, which might serve as a useful marker for the pter-p12 region of chromosome 20. PrP is associated with a variety of cognitive deficiencies and neurodegenerative diseases such as Creutzfeldt-Jakob disease, bovine spongiform encephalopathy, and kuru. The protein is highly conserved through mammals, lending credence to application of conclusions from test animals such as mice. Comparison between primates is especially similar, ranging from 92.9-99.6% similarity in amino acid sequences.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	An amino acid sequence from the middle region of human Prion protein (DYEDRYYRENMHRYPNQ) was used as the immunogen for this PrP antibody.
Isotype	IgG
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Uniprot	P04156

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the PrP antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	WB
Dilution	Weste blot: 0.5-1ug/ml

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17104432	R30892	100 ug	$419		Add to Cart

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