This gene is evolutionarily conserved, and its product is proposed to play a role in human cellular senescence and tumor suppression. Antiproliferative activity is reported to be localized to the 3' UTR, which is proposed to function as a trans-acting regulatory RNA. Several pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.
Categories
Primary Antibodies
Clonality
polyclonal
Host
Rabbit
Immunogen
prohibitin
Isotype
IgG
Molecular Weight
30 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
PHB, PHB1, prohibitin
Uniprot
P35232
Gene Id
5245
Research Area
Cell Division and Proliferation, Signal Transduction, Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)