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Home / Primary Antibodies / Polyclonal Antibodies

PRC1 antibody

SKU : BHA10806741

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Mfr.No.	FNab06749
Background	Key regulator of cytokinesis that cross-links antiparrallel microtubules at an average distance of 35 nM. Essential for controlling the spatiotemporal formation of the midzone and successful cytokinesis. Required for KIF14 localization to the central spindle and midbody. Required to recruit PLK1 to the spindle. Stimulates PLK1 phosphorylation of RACGAP1 to allow recruitment of ECT2 to the central spindle. Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression(PubMed:17409436).
Categories	Primary Antibodies
Clonality	polyclonal
Description	Key regulator of cytokinesis that cross-links antiparrallel microtubules at an average distance of 35 nM. Essential for controlling the spatiotemporal formation of the midzone and successful cytokinesis. Required for KIF14 localization to the central spindle and midbody. Required to recruit PLK1 to the spindle. Stimulates PLK1 phosphorylation of RACGAP1 to allow recruitment of ECT2 to the central spindle. Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression (PubMed:17409436).
Host	Rabbit
Immunogen	protein regulator of cytokinesis 1
Isotype	IgG
Molecular Weight	66 kDa
Reactivity	Human
Regulatory	RUO

Uniprot	O43663
Gene Id	9055
Research Area	Cell Division and Proliferation

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC
Description	ELISA ; WB ; IHC
Tested Application	WB: 1:500-1:2000; IHC: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10806741	FNab06749	100ug	$280		Add to Cart

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