This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap.
Categories
Primary Antibodies
Clonality
polyclonal
Host
Rabbit
Immunogen
progesterone receptor
Isotype
IgG
Molecular Weight
94 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
NR3C3, PGR, PR, progesterone receptor
Uniprot
P06401
Gene Id
5241
Research Area
Signal Transduction, Metabolism, Cancer, Immunology, Neuroscience
Weight
99kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)