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Home / Primary Antibodies / Polyclonal Antibodies

PPARA antibody

SKU : BHA10806655

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Mfr.No.	FNab06663
Alternative Names	NR1C1 ; PPAR
Background	Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine(16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl- 2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2.
Host	Rabbit
Immunogen	peroxisome proliferator-activated receptor alpha
Isotype	IgG
Molecular Weight	52-55 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	hPPAR, NR1C1, PPAR, PPAR alpha, PPARA

Uniprot	Q07869
Gene Id	5465
Research Area	Developmental biology, Signal Transduction, Metabolism, Cardiovascular, Neuroscience

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, IP
Description	ELISA ; WB ; IHC ; IP
Tested Application	WB: 1:200-1:1000; IHC: 1:50-1:200

Manual	FNab06663.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10806655	FNab06663	100ug	$240		Add to Cart

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