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Home / Primary Antibodies / Polyclonal Antibodies

PON2 antibody

SKU : BHA10806631

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Mfr.No.	FNab06639
Background	This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Capable of hydrolyzing lactones and a number of aromatic carboxylic acid esters. Has antioxidant activity. Is not associated with high density lipoprotein. Prevents LDL lipid peroxidation, reverses the oxidation of mildly oxidized LDL, and inhibits the ability of MM-LDL to induce monocyte chemotaxis.
Host	Rabbit
Immunogen	paraoxonase 2
Isotype	IgG
Molecular Weight	39 kDa
Reactivity	Human, Rat
Regulatory	RUO

Uniprot	Q15165
Gene Id	5445
Research Area	Cardiovascular, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IF, FC, IHC
Description	ELISA ; WB ; IF ; FC ; IHC
Tested Application	WB: 1:200 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab06639.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10806631	FNab06639	100ug	$280		Add to Cart

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