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Home / Primary Antibodies / Polyclonal Antibodies

POLR3K antibody

SKU : BHA10806626

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Mfr.No.	FNab06634
Alternative Names	RPC11
Background	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs(EBERs) induce type I interferon and NF-Kappa-B through the RIG-I pathway(By similarity).
Categories	Primary Antibodies
Clonality	polyclonal
Description	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).
Host	Rabbit
Immunogen	polymerase(RNA) III(DNA directed) polypeptide K, 12.3 kDa
Isotype	IgG
Molecular Weight	12 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	C11, C11 RNP3, hRPC11, HsC11p, My010, POLR3K, RNA polymerase III subunit C10, RNA polymerase III subunit C11, RPC10, RPC11, RPC12.5

Uniprot	Q9Y2Y1
Gene Id	51728
Research Area	Immunology, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, IHC, IF, WB
Description	ELISA ; IHC ; IF ; WB
Tested Application	WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:50-1:500

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SKU	Supplier No.	Size	Your price	Quantity
BHA10806626	FNab06634	100ug	$240		Add to Cart

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