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Home / Primary Antibodies / Polyclonal Antibodies

PNKP antibody

SKU : BHA10806575

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Mfr.No.	FNab06583
Background	This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Plays a key role in the repair of DNA damage, functioning as part of both the non-homologous end-joining (NHEJ) and base excision repair (BER) pathways. Through its two catalytic activities, PNK ensures that DNA termini are compatible with extension and ligation by either removing 3'-phosphates from, or by phosphorylating 5'-hydroxyl groups on, the ribose sugar of the DNA backbone.
Host	Rabbit
Immunogen	polynucleotide kinase 3'-phosphatase
Isotype	IgG
Molecular Weight	57 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO

Uniprot	Q96T60
Gene Id	11284
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB
Description	ELISA ; WB
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

Manual	FNab06583.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10806575	FNab06583	100ug	$240		Add to Cart

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