Guanine nucleotide exchange factor that activates RHOA and maybe the NF-kappa-B signaling pathway. Involved in the control of neuronal cell differentiation. Plays a role in angiogenesis through regulation of endothelial cells chemotaxis.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Guanine nucleotide exchange factor that activates RHOA and maybe the NF-kappa-B signaling pathway. Involved in the control of neuronal cell differentiation. Plays a role in angiogenesis through regulation of endothelial cells chemotaxis.
Host
Rabbit
Immunogen
pleckstrin homology domain containing, family G(with RhoGef domain) member 5
Isotype
IgG
Molecular Weight
105-125 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
KIAA0720
Antigen
PLEKHG5
Uniprot
O94827
Gene Id
57449
Research Area
Signal Transduction, Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)