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Home / Primary Antibodies / Polyclonal Antibodies

PKM antibody

SKU : BHA10806484

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Mfr.No.	FNab06492
Alternative Names	OIP3 ; PK2 ; PK3 ; PKM2
Background	Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate(PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio betwween the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio betwween the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival.
Host	Rabbit
Immunogen	PKM2 pyruvate kinase, muscle
Isotype	IgG
Molecular Weight	58 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	OIP3, PK2, PK3, PKM2

Uniprot	P14618
Gene Id	5315
Research Area	Stem Cells, Cancer, Cardiovascular, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, IHC, WB
Description	ELISA ; IHC ; WB
Tested Application	WB: 1:500-1:2000; IHC: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10806484	FNab06492	100ug	$260		Add to Cart

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