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Home / Primary Antibodies / Polyclonal Antibodies

PKC beta antibody

SKU : BHA10806473

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Mfr.No.	FNab06481
Alternative Names	PKCB ; PKCbeta ; PKCB ; PRKCB ; PRKCB1 ; PRKCB2 ; ProteinkinaseCbetatype ; proteinkinaseC ; beta
Background	Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Categories	Primary Antibodies
Cellular Localization	Cytoplasm, Membrane, Nucleus
Clonality	polyclonal
Host	Rabbit
Immunogen	protein kinase C, beta
Isotype	IgG
Molecular Weight	80 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	Cytoplasm, Membrane, Nucleus
Synonyms	PKC B, PKC beta, PKCB, PRKCB, PRKCB1, PRKCB2, Protein kinase C beta type, protein kinase C, beta

Uniprot	P05771
Gene Id	5579
Research Area	Immunology, Cardiovascular, Metabolism, Signal Transduction
Weight	77kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC, IP

Description

ELISA ; WB ; IHC ; IP

Dilution

WB	1:500-1:5000
IP	1:500-1:5000
IHC	1:20-1:200

Tested Application

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab06481.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10806473	FNab06481	100ug	$260		Add to Cart

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