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Home / Primary Antibodies / Polyclonal Antibodies

PITRM1 antibody

SKU : BHA10806464

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Mfr.No.	FNab06472
Alternative Names	KIAA1104 ; MP1
Background	The protein encoded by this gene is an ATP-dependent metalloprotease that degrades post-cleavage mitochondrial transit peptides. The encoded protein binds zinc and can also degrade amyloid beta A4 protein, suggesting a possible role in Alzheimer's disease.
Categories	Primary Antibodies
Clonality	polyclonal
Description	ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference.
Host	Rabbit
Immunogen	pitrilysin metallopeptidase 1
Isotype	IgG
Molecular Weight	117 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	KIAA1104, MP1

Uniprot	Q5JRX3
Gene Id	10531
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB
Description	ELISA ; WB
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab06472.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10806464	FNab06472	100ug	$260		Add to Cart

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