Microtubule-binding protein essential for faithful chromosome segregation. Mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Microtubule-binding protein essential for faithful chromosome segregation. Mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor.
Host
Rabbit
Immunogen
PIN2-interacting protein 1
Isotype
IgG
Molecular Weight
40 kDa
Reactivity
Human
Regulatory
RUO
Synonyms
LPTL, LPTS
Uniprot
Q96BK5
Gene Id
54984
Research Area
Cancer
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)