The protein encoded by this gene contains more than thirty transmembrane domains and likely functions as part of mechanically-activated (MA) cation channels. These channels serve to connect mechanical forces to biological signals. The encoded protein quickly adapts MA currents in somatosensory neurons. Defects in this gene are a cause of type 5 distal arthrogryposis. Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
Clonality
polyclonal
Host
Rabbit
Immunogen
Piezo-type mechanosensitive ion channel component 2
Immunogen Region
Piezo-type mechanosensitIVe ion channel component 2
Isotype
IgG
Reactivity
Human
Recommended Dilution
IHC: 1:50-1:200
Synonyms
DA3, DA5, MWKS, DAIPT, FAM38B
Uniprot
Q9H5I5
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Tested Application
IHC: 1:50-1:200
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10482.pdf" target="_blank">Data Sheet</ a>