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Home / Primary Antibodies / Polyclonal Antibodies

Phospho-VEGF Receptor 2 (Y1175) antibody

SKU : BHA10809953

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Mfr.No.	FNab09964
Background	KDR, also named as VEGFR-2, FLK1 and CD309, is a receptor for VEGF or VEGFC. KDR which belongs to the protein kinase superfamily, has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. KDR functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. Mutations of this gene are implicated in infantile capillary hemangiomas.
Clonality	polyclonal
Host	Rabbit
Immunogen	A phospho specific peptide corresponding to residues surrounding Y1175 of human VEGF Receptor 2
Immunogen Region	A phospho specific peptide corresponding to residues surrounding Y1175 of human VEGF Receptor 2
Isotype	IgG
Molecular Weight	250 kDa
Reactivity	Human, Mouse, Rat
Recommended Dilution	WB: 1:500 - 1:1000; IHC: 1:50 - 1:100
Synonyms	CD309, Fetal liver kinase 1, FLK 1, FLK1, KDR, Kinase insert domain receptor, VEGF Receptor 2, VEGFR, VEGFR 2, VEGFR2

Uniprot	P35968
Gene Id	3791

Form	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Tested Application	WB: 1:500 - 1:1000; IHC: 1:50 - 1:100

Product Manual	<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab09964.pdf" target="_blank">Data Sheet</ a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809953	FNab09964	100ug	$260		Add to Cart

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