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Home / Primary Antibodies

Phospho-STAT5 (Ser725/Ser730)[Ser726/Ser731] Antibody

SKU : BHA12900669

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AFFINITY BIOSCIENCES LTD

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Mfr.No.	AF3304
Alternative Names	Mammary gland factor ; MGF ; Signal transducer and activator of transcription 5A ; STA5A_HUMAN ; STAT 5 ; STAT 5A ; STAT5 ; STAT5A ; Signal transducer and activator of transcription 5B ; STA5B_HUMAN ; STAT5 ; Stat5b ; Transcription factor STAT5B ;
Categories	Primary Antibodies ; Phospho Antibodies
Clonality	polyclonal
Description	STAT5B transcription factor of the STAT family. Phosphorylated and activated by receptor-associated kinases triggered by cytokines including IL2, IL3, GM-CSF, and various growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression.
Immunogen	A synthesized peptide derived from human STAT5A/B around the phosphorylation site of Serine 725/730.
Molecular Weight	Observed Mol.Wt.: 90kDa. Predicted Mol.Wt.: 91kDa.
Reactivity	Human, Mouse, Rat
Specificity	Phospho-STAT5A/B (Ser725/730) Antibody detects endogenous levels of STAT5A/B only when phosphorylated at Serine 725/730.
Subcellular Location	Cytoplasm. Nucleus. Translocated into the nucleus in response to phosphorylation.

Antigen

Phospho-STAT5A/B (Ser725/730)

Uniprot

P42229 ; P51692

Gene Id

67776776

Sequence

10	20	30	40	50
MAGWIQAQQL	QGDALRQMQV	LYGQHFPIEV	RHYLAQWIES	QPWDAIDLDN
60	70	80	90	100
PQDRAQATQL	LEGLVQELQK	KAEHQVGEDG	FLLKIKLGHY	ATQLQKTYDR
110	120	130	140	150
CPLELVRCIR	HILYNEQRLV	REANNCSSPA	GILVDAMSQK	HLQINQTFEE
160	170	180	190	200
LRLVTQDTEN	ELKKLQQTQE	YFIIQYQESL	RIQAQFAQLA	QLSPQERLSR
210	220	230	240	250
ETALQQKQVS	LEAWLQREAQ	TLQQYRVELA	EKHQKTLQLL	RKQQTIILDD
260	270	280	290	300
ELIQWKRRQQ	LAGNGGPPEG	SLDVLQSWCE	KLAEIIWQNR	QQIRRAEHLC
310	320	330	340	350
QQLPIPGPVE	EMLAEVNATI	TDIISALVTS	TFIIEKQPPQ	VLKTQTKFAA
360	370	380	390	400
TVRLLVGGKL	NVHMNPPQVK	ATIISEQQAK	SLLKNENTRN	ECSGEILNNC
410	420	430	440	450
CVMEYHQATG	TLSAHFRNMS	LKRIKRADRR	GAESVTEEKF	TVLFESQFSV
460	470	480	490	500
GSNELVFQVK	TLSLPVVVIV	HGSQDHNATA	TVLWDNAFAE	PGRVPFAVPD
510	520	530	540	550
KVLWPQLCEA	LNMKFKAEVQ	SNRGLTKENL	VFLAQKLFNN	SSSHLEDYSG
560	570	580	590	600
LSVSWSQFNR	ENLPGWNYTF	WQWFDGVMEV	LKKHHKPHWN	DGAILGFVNK
610	620	630	640	650
QQAHDLLINK	PDGTFLLRFS	DSEIGGITIA	WKFDSPERNL	WNLKPFTTRD
660	670	680	690	700
FSIRSLADRL	GDLSYLIYVF	PDRPKDEVFS	KYYTPVLAKA	VDGYVKPQIK
710	720	730	740	750
QVVPEFVNAS	ADAGGSSATY	MDQAPSPAVC	PQAPYNMYPQ	NPDHVLDQDG
760	770	780	790
EFDLDETMDV	ARHVEELLRR	PMDSLDSRLS	PPAGLFTSAR	GSLS

Concentration	1mg/ml
Format	Liquid
Purification	The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Storage Condition	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.

Applications	IF/ICC, ELISA, IHC, WB
Dilution	WB 1:500-1:2000 IHC 1:50-1:200 IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Manual
MSDS
IHC Protocol.
Western Blotting Handbook.

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SKU	Supplier No.	Size	Your price	Quantity
BHA12900669	AF3304	100ul	$280		Add to Cart
BHA12900669	AF3304	200ul	$350		Add to Cart

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