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Home / Primary Antibodies / Polyclonal Antibodies

Phospho-MAPK14 (T180/Y182) antibody

SKU : BHA10810104

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Mfr.No.	FNab10117
Background	The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Clonality	polyclonal
Host	Rabbit
Immunogen	A synthetic phosphorylated peptide around T180 & Y182 of human p38 MAPK
Immunogen Region	A synthetic phosphorylated peptide around T180 & Y182 of human p38 MAPK
Isotype	IgG
Molecular Weight	41kDa
Reactivity	Human
Recommended Dilution	WB: 1:500-1:2000
Synonyms	CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA

Uniprot	Q16539
Gene Id	1432
Research Area	epigenetics, Cancer, Immunology, Signal Transduction

Form	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Tested Application	WB: 1:500-1:2000

Product Manual	<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10117.pdf" target="_blank">Data Sheet</ a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA10810104	FNab10117	100ug	$280		Add to Cart

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