This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms.
Clonality
polyclonal
Host
Rabbit
Immunogen
Phospho-CREB1-S133
Immunogen Region
Phospho-CREB1-S133
Isotype
IgG
Molecular Weight
42kDa
Reactivity
Human
Recommended Dilution
WB: 1:500 - 1:2000; IF: 1:50 - 1:200
Synonyms
CREB, CREB-1
Uniprot
P16220
Gene Id
1385
Research Area
Developmental biology, Signal Transduction, Metabolism, Cardiovascular, Immunology, Cancer, Neuroscience
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Tested Application
WB: 1:500 - 1:2000; IF: 1:50 - 1:200
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab09948.pdf" target="_blank">Data Sheet</ a>