The serine-threonine protein kinase AKT1 is catalytically inactive in serum-starved primary and immortalized fibroblasts. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. This antibody detects all the members of AKT with phospho-modification.
Categories
Primary Antibodies ; Phospho Antibodies
Clonality
monoclonal
Host
Mouse
Immunogen
v-akt murine thymoma viral oncogene homolog 1
Isotype
IgG1
Molecular Weight
60KD
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
AKT, AKT1, AKT1-phospho-S473, PKB, PKB ALPHA, PRKBA, Protein kinase B, Proto oncogene c Akt, RAC, RAC ALPHA, RAC PK alpha