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Home / Primary Antibodies / Polyclonal Antibodies

PHF19 antibody

SKU : BHA10806375

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Mfr.No.	FNab06383
Alternative Names	PCL3
Categories	Primary Antibodies
Clonality	polyclonal
Description	Polycomb group (PcG) that specifically binds histone H3 trimethylated at 'Lys-36' (H3K36me3) and recruits the PRC2 complex. Probably involved in the transition from an active state to a repressed state in embryonic stem cells: acts by binding to H3K36me3, a mark for transcriptional activation, and recruiting H3K36me3 histone demethylases NO66 or KDM2B, leading to demethylation of H3K36 and recruitment of the PRC2 complex that mediates H3K27me3 methylation, followed by de novo silencing. Recruits the PRC2 complex to CpG islands and contributes to embryonic stem cell self-renewal. Also binds dimethylated at 'Lys- 36' (H3K36me2). Isoform 1 and isoform 2 inhibit transcription from an HSV-tk promoter.
Host	Rabbit
Immunogen	PHD finger protein 19
Isotype	IgG
Molecular Weight	66 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	PCL3

Uniprot	Q5T6S3
Gene Id	26147
Research Area	Developmental biology, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, IP, IF, WB
Description	ELISA ; IP ; IF ; WB
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab06383.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10806375	FNab06383	100ug	$260		Add to Cart

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