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Home / Primary Antibodies / Polyclonal Antibodies

PGK1 antibody

SKU : BHA10806346

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Mfr.No.	FNab06354
Alternative Names	PGKA
Background	The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1, 3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. Additionally, this protein is secreted by tumor cells where it participates in angiogenesis by functioning to reduce disulfide bonds in the serine protease, plasmin, which consequently leads to the release of the tumor blood vessel inhibitor angiostatin. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Deficiency of the enzyme is associated with a wide range of clinical phenotypes hemolytic anemia and neurological impairment. Pseudogenes of this gene have been defined on chromosomes 19, 21 and the X chromosome.
Categories	Primary Antibodies
Clonality	polyclonal
Description	In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein) (PubMed:2324090). May play a role in sperm motility (PubMed:26677959).
Host	Rabbit
Immunogen	phosphoglycerate kinase 1
Isotype	IgG
Molecular Weight	47 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	PGKA

Uniprot	P00558
Gene Id	5230
Research Area	Cardiovascular, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC
Description	ELISA ; WB ; IHC
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

Manual	FNab06354.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10806346	FNab06354	100ug	$260		Add to Cart

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