Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
Categories
Primary Antibodies
Clonality
monoclonal
Description
Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
Host
Mouse
Immunogen
profilin 2
Isotype
IgG1
Molecular Weight
15 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
D3S1319E, PFL, PFN2, Prifilin 2, PROF2, profilin 2, Profilin II
Uniprot
P35080
Gene Id
5217
Clone No
5D4
Research Area
Neuroscience
Form
liquid
Format
liquid
Purification
Protein A+G purification
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)