Acts as a regulatory protein that associates with GUCY2C and negatively modulates its heat-stable enterotoxin-mediated activation. Stimulates SLC9A3 activity in the presence of elevated calcium ions.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Acts as a regulatory protein that associates with GUCY2C and negatively modulates its heat-stable enterotoxin-mediated activation. Stimulates SLC9A3 activity in the presence of elevated calcium ions.
Host
Rabbit
Immunogen
PDZ domain containing 3
Isotype
IgG
Molecular Weight
54-60KD
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
IKEPP, NHERF4, PDZK2
Uniprot
Q86UT5
Gene Id
79849
Research Area
Signal Transduction
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)