Regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Plays a role in androgen-induced proliferative arrest in prostate cells.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Plays a role in androgen-induced proliferative arrest in prostate cells.
Host
Rabbit
Immunogen
PDS5, regulator of cohesion maintenance, homolog B
Isotype
IgG
Molecular Weight
165-170KD
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
APRIN, AS3,
Uniprot
Q9NTI5
Gene Id
23047
Research Area
Cell Division and Proliferation, Developmental biology
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)