May function as a scaffold on which the coordinated assembly of proteins can occur. May play a role as an adapter that, via its PDZ domain, localizes LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Involved in both of the two fundamental mechanisms of bone formation, direct bone formation(e.g. embryonic flat bones mandible and cranium), and endochondral bone formation(e.g. embryonic long bone development). Plays a role during fracture repair. Involved in BMP6 signaling pathway(By similarity).
Categories
Primary Antibodies
Clonality
polyclonal
Description
May function as a scaffold on which the coordinated assembly of proteins can occur. May play a role as an adapter that, via its PDZ domain, localizes LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Involved in both of the two fundamental mechanisms of bone formation, direct bone formation (e.g. embryonic flat bones mandible and cranium), and endochondral bone formation (e.g. embryonic long bone development). Plays a role during fracture repair. Involved in BMP6 signaling pathway (By similarity).
Host
Rabbit
Immunogen
PDZ and LIM domain 7(enigma)
Isotype
IgG
Molecular Weight
55KD
Reactivity
Human
Regulatory
RUO
Synonyms
ENIGMA
Uniprot
Q9NR12
Gene Id
9260
Research Area
Developmental biology
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)