Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP(PubMed:9714779, PubMed:15489334). Specifically regulates nitric-oxide-generated cGMP(PubMed:15489334).
Categories
Primary Antibodies
Clonality
polyclonal
Description
Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'- GMP (PubMed:9714779, PubMed:15489334). Specifically regulates nitric-oxide-generated cGMP (PubMed:15489334).
Host
Rabbit
Immunogen
phosphodiesterase 5A, cGMP-specific
Isotype
IgG
Molecular Weight
100KD
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
PDE5
Uniprot
O76074
Gene Id
8654
Research Area
Developmental biology, Cardiovascular, Metabolism, Signal Transduction
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)