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Home / Primary Antibodies / Polyclonal Antibodies

PCM1 antibody

SKU : BHA10806204

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Mfr.No.	FNab06212
Background	The protein encoded by this gene is a component of centriolar satellites, which are electron dense granules scattered around centrosomes. Inhibition studies show that this protein is essential for the correct localization of several centrosomal proteins, and for anchoring microtubules to the centrosome. Chromosomal aberrations involving this gene are associated with papillary thyroid carcinomas and a variety of hematological malignancies, including atypical chronic myeloid leukemia and T-cell lymphoma. Multiple transcript variants encoding different isoforms have been found for this gene.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Required for centrosome assembly and function. Essential for the correct localization of several centrosomal proteins including CEP250, CETN3, PCNT and NEK2. Required to anchor microtubules to the centrosome. Involved in the biogenesis of cilia.
Host	Rabbit
Immunogen	pericentriolar material 1
Isotype	IgG
Molecular Weight	300 kDa
Reactivity	Human, Mouse
Regulatory	RUO

Uniprot	Q15154
Gene Id	5108
Research Area	Epigenetics

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IP, IHC
Description	ELISA ; WB ; IP ; IHC
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab06212.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10806204	FNab06212	100ug	$260		Add to Cart

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