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Home / Primary Antibodies / Polyclonal Antibodies

PCK1 antibody

SKU : BHA10806202

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Mfr.No.	FNab06210
Alternative Names	PEPCK1
Background	This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
Host	Rabbit
Immunogen	phosphoenolpyruvate carboxykinase 1 (soluble)
Isotype	IgG
Molecular Weight	69 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	PEPCK1

Uniprot	P35558
Gene Id	5105
Research Area	Cardiovascular, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IP
Description	ELISA ; WB ; IP
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab06210.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10806202	FNab06210	100ug	$240		Add to Cart

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