Involved in the base excision repair(BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.
Host
Rabbit
Immunogen
poly(ADP-ribose) polymerase 2
Isotype
IgG
Molecular Weight
66 kDa
Reactivity
Human, Mouse
Regulatory
RUO
Synonyms
ADPRT2, ADPRTL2
Uniprot
Q9UGN5
Gene Id
10038
Research Area
Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)