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Home / Primary Antibodies / Polyclonal Antibodies

PAR2 antibody

SKU : BHA10810511

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Mfr.No.	FNab10720
Background	Proteinase-activated receptors(PARs) are G protein-coupled receptors activated through cleavage of their N-termini by mainly serine proteases. The family of PARs include four members: PAR1, PAR2, PAR3 and PAR4. PAR2, also known as F2RL1, is expressed in epithelial cells(e.g., lung, gastrointestinal tract), endothelial cells, smooth muscle cells, fibroblasts, nerves, and some immune and inflammatory cells. PAR2 knockout mice and PAR2 agonists and antagonists have implicated PAR2 as a promising target in inflammatory conditions; respiratory, gastrointestinal, metabolic, cardiovascular, and neurological dysfunction; and cancers.(PMID:23895492)
Clonality	polyclonal
Host	Rabbit
Immunogen	coagulation factor II(thrombin) receptor-like 1
Immunogen Region	coagulation factor II(thrombin) receptor-like 1
Isotype	IgG
Molecular Weight	50 kDa
Reactivity	Human
Recommended Dilution	IHC: 1:20-1:200
Synonyms	F2RL1, G protein coupled receptor 11, GPR11, PAR 2, PAR2, Thrombin receptor like 1

Uniprot	P55085

Form	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Tested Application	IHC: 1:20-1:200

Product Manual	<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10720.pdf" target="_blank">Data Sheet</ a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA10810511	FNab10720	100ug	$240		Add to Cart

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