This gene encodes a member of the lipase family of proteins. The encoded enzyme is secreted by the pancreas and hydrolyzes triglycerides in the small intestine, and is essential for the efficient digestion of dietary fats. Inhibition of the encoded enzyme may prevent high-fat diet-induced obesity in mice and result in weight loss in human patients with obesity. Mutations in this gene cause congenital pancreatic lipase deficiency, a rare disorder characterized by steatorrhea.
Categories
Primary Antibodies
Clonality
polyclonal
Host
Rabbit
Immunogen
pancreatic lipase
Isotype
IgG
Molecular Weight
55 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
Lipase, Pancreatic Lipase, PL, PNLIP, PTL
Uniprot
P16233
Gene Id
5406
Research Area
Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)