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Home / Antibodies

Pan Methylated Lysine Monoclonal Antibody (Mix)

SKU : BHA13715124

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Abbkine Scientific Co., Ltd.

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Mfr.No.	ABM0060
Alternative Names	Lysine
Background	Methylation of lysine residues is a common regulatory posttranslational modification (PTM) that results in the mono-, di-, or tri-methylation of lysine at epsilon-amine groups by protein lysine methyltransferases (PKMTs). Two PKMT groups are recognized based on structure and catalytic mechanism: class I methyltransferases or seven beta strand enzymes, and SET domain-containing class V methyltransferases. Both use the methyl donor S-adenosyl-L-methionine to methylate histone and non-histone proteins. Class I methyltransferases methylate amino acids, DNA, and RNA. Six methyl-lysine-interacting protein families are distinguished based on binding domains: mBT, PHD finger, Tudor, PWWP, WD40 repeat, and chromodomains. Many of these display differential binding preferences based on lysine methylation state. KDM1 subfamily lysine demethylases catalyze demethylation of mono- and di-methyl lysines, while 2-oxoglutarate-dependent JmjC (KDM2-7) subfamily enzymes also modify tri-methyl lysine residues.
Clonality	Monoclonal
Conjugate	The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen
Description	Mouse Anti-Pan Methylated Lysine Monoclonal Antibody (Mix)
Formulation	The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen, Liquid solution
Host	Mouse
Immunogen	Conjugated Protein
Immunogen Region	Conjugated Protein
Isotype	Mouse IgG1
Others	The antibody detects endogenous Pan Methylated Lysine protein.
Precautions	The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Reactivity	All
Tag	Lysine
Note	Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:1000-1:2000), IHC-P (1:200-1:500).

Concentration	1 mg/ml, 1 mg/ml
Purification	The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen, The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen
Storage Buffer	PBS, pH 7.4, containing 0.02% Sodium Azide as preservative and 50% Glycerol.
Storage Instructions	Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Applications	WB, IHC-P

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA13715124	ABM0060	100 uL	$229		Add to Cart

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