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Home / Primary Antibodies / Polyclonal Antibodies

P53 antibody

SKU : BHA10806075

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Mfr.No.	FNab06083
Alternative Names	AntigenNYCO13 ; Cellulartumorantigenp53 ; FLJ92943 ; LFS1 ; P53 ; Phosphoproteinp53 ; TP53 ; TRP53 ; tumorproteinp53 ; Tumorsuppressorp53
Background	This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277).
Categories	Primary Antibodies
Clonality	polyclonal
Description	TP53, also named as P53 and NY-CO-13, belongs to the p53 family. It has 9 isoforms. In SDS-Page, the MW is about 53kd. TP53 acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. It is involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. The antibody reacts specifically with 53 kDa protein.
Host	Rabbit
Immunogen	tumor protein p53
Isotype	IgG
Molecular Weight	53 kDa
Reactivity	Human, Rat, Mouse
Regulatory	RUO
Synonyms	Antigen NY CO 13, Cellular tumor antigen p53, FLJ92943, LFS1, P53, Phosphoprotein p53, TP53, TRP53, tumor protein p53, Tumor suppressor p53

Uniprot	P04637
Gene Id	7157
Research Area	Epigenetics, Cell Division and Proliferation, Metabolism, Immunology, Cancer, Stem Cells, Neuroscience
Weight	53kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications

ELISA, IHC, IP, WB, IF

Description

ELISA ; IHC ; IP ; WB ; IF

Dilution

WB	1:500-1:5000
IP	1:500-1:5000
IHC	1:500-1:2000
IF	1:20-1:200

Tested Application

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:20 - 1:100

Manual	FNab06083.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10806075	FNab06083	100ug	$240		Add to Cart

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