Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells.
Host
Rabbit
Immunogen
purinergic receptor P2X, ligand-gated ion channel, 7
Isotype
IgG
Molecular Weight
40-68 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
P2RX7, P2X7, P2X purinoceptor 7
Uniprot
Q99572
Gene Id
5028
Research Area
Signal Transduction, Neuroscience
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)