Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells.
Clonality
polyclonal
Host
Rabbit
Immunogen
purinergic receptor P2X, ligand-gated ion channel, 7
Immunogen Region
purinergic receptor P2X, ligand-gated ion channel, 7
Isotype
IgG
Reactivity
Human
Recommended Dilution
IHC: 1:20-1:200
Synonyms
P2RX7, P2X7, P2X purinoceptor 7
Uniprot
Q99572
Gene Id
5028
Research Area
Signal Transduction, Neuroscience
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Tested Application
IHC: 1:20-1:200
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10078.pdf" target="_blank">Data Sheet</ a>