Lectin which functions in endoplasmic reticulum(ER) quality control and ER-associated degradation(ERAD). May bind terminally misfolded non-glycosylated proteins as well as improperly folded glycoproteins, retain them in the ER, and possibly transfer them to the ubiquitination machinery and promote their degradation. Possible targets include TRPV4.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Lectin which functions in endoplasmic reticulum (ER) quality control and ER-associated degradation (ERAD). May bind terminally misfolded non-glycosylated proteins as well as improperly folded glycoproteins, retain them in the ER, and possibly transfer them to the ubiquitination machinery and promote their degradation. Possible targets include TRPV4.
Host
Rabbit
Immunogen
osteosarcoma amplified 9, endoplasmic reticulum associated protein
Isotype
IgG
Molecular Weight
73kd
Reactivity
Human
Regulatory
RUO
Uniprot
Q13438
Gene Id
10956
Research Area
Cardiovascular
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)