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Home / Primary Antibodies / Polyclonal Antibodies

OMA1 antibody

SKU : BHA10805983

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Mfr.No.	FNab05991
Alternative Names	MPRP1
Background	Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion. May also cleave UQCC3 under these conditions. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion. May also cleave UQCC3 under these conditions. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions.
Host	Rabbit
Immunogen	OMA1 homolog, zinc metallopeptidase
Isotype	IgG
Molecular Weight	60 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	MPRP1

Antigen	OMA1
Uniprot	Q96E52
Gene Id	115209
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB
Description	ELISA ; WB
Tested Application	WB: 1:500-1:2000

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SKU	Supplier No.	Size	Your price	Quantity
BHA10805983	FNab05991	100ug	$260		Add to Cart

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