Involved in transforming growth factor beta(TGF-beta)-induced smooth muscle differentiation. TGF-beta induces expression and nuclear translocation of OLFM2 where it binds to SRF, causing its dissociation from the transcriptional repressor HEY2/HERP1 and facilitating binding of SRF to target genes(PubMed:25298399). Plays a role in AMPAR complex organization(By similarity).
Categories
Primary Antibodies
Clonality
polyclonal
Description
Involved in transforming growth factor beta (TGF-beta)- induced smooth muscle differentiation. TGF-beta induces expression and nuclear translocation of OLFM2 where it binds to SRF, causing its dissociation from the transcriptional repressor HEY2/HERP1 and facilitating binding of SRF to target genes (PubMed:25298399). Plays a role in AMPAR complex organization (By similarity).
Host
Rabbit
Immunogen
olfactomedin 2
Isotype
IgG
Molecular Weight
51kd
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
NOE2
Uniprot
O95897
Gene Id
93145
Research Area
Developmental biology, Signal Transduction
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)