It has 3 isoforms produced by alternative splicing. This antibody is specific to NXN.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Functions as a redox-dependent negative regulator of the Wnt signaling pathway, possibly by preventing ubiquitination of DVL3 by the BCR(KLHL12) complex. May also function as a transcriptional regulator act as a regulator of protein phosphatase 2A (PP2A) (By similarity).
Host
Rabbit
Immunogen
nucleoredoxin
Isotype
IgG
Molecular Weight
48 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
NRX, nucleoredoxin, NXN, TRG 4
Uniprot
Q6DKJ4
Gene Id
64359
Research Area
Developmental biology, Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)