Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements(CTE) and in the export of mRNA from the nucleus to the cytoplasm(TAP/NFX1 pathway). The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5 components of the TREX complex. ALYREF/THOC4-bound mRNA is thought to be transferred to the NXF1-NXT1 heterodimer for export.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements (CTE) and in the export of mRNA from the nucleus to the cytoplasm (TAP/NFX1 pathway). The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5 components of the TREX complex. ALYREF/THOC4-bound mRNA is thought to be transferred to the NXF1-NXT1 heterodimer for export.
Host
Rabbit
Immunogen
nuclear RNA export factor 1
Isotype
IgG
Molecular Weight
66-70 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
MEX67, mRNA export factor TAP, nuclear RNA export factor 1, NXF1, TAP, Tip associated protein, Tip associating protein
Uniprot
Q9UBU9
Gene Id
10482
Research Area
Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IF
Description
ELISA ; WB ; IF
Tested Application
WB : 1:500-1:1000; IHC : 1:20-1:200; IF : 1:20-1:200