The protein encoded by this gene is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Seems to promote the survival of visceral and proprioceptive sensory neurons.
Host
Rabbit
Immunogen
neurotrophin 3
Isotype
IgG
Molecular Weight
29 kDa
Reactivity
Human, Mouse
Regulatory
RUO
Synonyms
HDNF
Uniprot
P20783
Gene Id
4908
Research Area
Signal Transduction
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)